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TABLE 1 Antituberculous medications known to be CYP450 enzyme system substrates or can impact its metabolic activity, possible effects of tobacco smoke compounds, and resulting potential interactions

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Large positive ROSs correspond to strong and consistent evidence of an association, while small positive ROSs and negative ROSs reflect weak evidence for an association, based on the available data

To clarify the effects of maternal smoking intensity, the association between maternal smoking intensity (number of cigarettes, duration of smoking) and bronchial asthma at 3 years of age was subjected to logistic regression analysis (Table 2)